I do the first oil change at around 140 miles and try to get at least 6 to 8 hours on it. I use Mobile one 10w40 synthetic motorcycle oil. Any major brand synthetic motorcycle oil may have better protection if your engine overheats. The regular Honda GN4 10W-30 will protect the engine. The important part is to change it on time and occasionally I do go 100 miles over. Super clean air and clean oil will help these engines go to over 50,000 miles. The aftermarket prefilter in clean air helps the engine life. Since the 6-speed gearbox uses the engine oil it is important to use a motorcycle oil that has the additives for the transmission. The Talon engine has the under-piston oil jets and a larger cooling system for the optional Turbo. Without the turbo the engine life is increased.