Yup a 22 will kill a deer, some rounds are just more efficient than others.I know people that use a .223 to hunt deer. In SD that’s the minimum caliber.
It takes a really well placed shot to bring them down without running off too.
I'd rather have a quick clean takedown, no point in making the animal suffer. Also I am fat and out of shape so searching for one in the brush and thickets we have around here is not enjoyable. Im in it for the meat not the sport.